What are the symptoms of macrocytosis?
Mild macrocytosis produces no symptoms. Symptoms of moderate macrocytosis include fatigue and weakness, problems with digestion, and neurological symptoms. Neurological symptoms, such as confusion, depression, or numbness, may indicate nerve damage from persistent macrocytosis, which should be treated as quickly as possible to prevent further damage.
Common symptoms of macrocytosis
You may experience macrocytosis symptoms daily or just once in a while. At times, any of these symptoms can be severe:
- Bleeding gums
- Difficulty concentrating
- Pale skin or pallor
- Shortness of breath
- Swollen tongue
Symptoms that might indicate a serious condition
Left untreated, macrocytosis can lead to neurological complications that may become permanent. Seek prompt medical care if you, or someone you are with, have any of these serious symptoms including:
- Loss of balance
- Numbness or tingling of arms or legs
What is macrocytosis?
Macrocytosis, or megaloblastic anemia, is a blood condition characterized by insufficient and unusually large red blood cells. The lack of viable red blood cells leads to oxygen deficiency throughout the body. Over time, this lack of oxygen can cause symptoms related to many organ systems.... Read more about macrocytosisintroduction
What causes macrocytosis?
Usually, macrocytosis is caused by nutritional deficiency, specifically of folate or vitamin B12. This can arise from a hereditary condition called pernicious anemia, in which a protein called intrinsic factor is lacking in your gut. Intrinsic factor helps your body absorb vitamin B12. Vitamin B12 is essential for replenishing folate, which is required by your body to make red blood cells.... Read more about macrocytosiscauses
How is macrocytosis treated?
For mild cases of macrocytosis, no treatment may be required. The treatment of macrocytosis depends on its cause. For cases directly linked to vitamin B12 deficiency, injections of the vitamin can be given. For mild cases, oral supplements may be prescribed, along with a balanced diet. For cases in which macrocytosis is related to another condition, such as celiac disease or Crohn’s disease, vitamin B12 injections can be given until the underlying cause of the deficiency has been treated. In some cases, it may be necessary to take vitamin B12 injections on a long-term basis.... Read more about macrocytosistreatments