What causes lupus?

Lupus is an autoimmune disease. In an autoimmune disease, the body’s immune system mistakes healthy tissues and organs as dangerous invaders in the body and attacks them. This results in inflammation that can eventually damage and destroy the affected tissues and organs. What causes this autoimmune response in the body is not known, but it is thought that lupus is triggered by various environmental factors and possibly a genetic predisposition for developing an autoimmune disorder. In some cases, an individual who develops lupus has a relative with lupus or another autoimmune disease.

What are the risk factors for lupus?

A number of factors are linked to an increased risk of developing lupus. Not all people with risk factors will develop lupus. Risk factors for lupus include:

  • Family history of lupus

  • Female gender between ages 15 and 44

  • Hispanic, American Indian, Pacific Islander, or African American descent

  • Use of beta blockers, which are commonly used to treat heart disease and hypertension

INTRODUCTION

What is lupus?

Lupus is a chronic disease that can have a serious and widespread effect on the body including the skin, joints, muscles, and other organs. However, in many cases, lupus is a mild disease that can be successfully controlled with regular medical care. About 1.5 million Americans have lupus, and about 90 percent of people with lupus are women, according to the Lupus Foundation of America (So... Read more about lupus introduction

SYMPTOMS

What are the symptoms of lupus?

Symptoms of lupus are the result of tissue inflammation throughout various parts of the body. The type and severity of symptoms vary between individuals and the type of lupus. However, lupus generally occurs as periodic attacks of symptoms. These symptom flare-ups are followed by periods of time in which symptoms improve.... Read more about lupus symptoms

TREATMENTS

How is lupus treated?

There is no cure for lupus. However, it is a myth that lupus is commonly a fatal disease. With early recognition, regular medical care, and good patient compliance with a treatment plan, it is possible for most people with lupus to live a normal life.... Read more about lupus treatments

Medical Reviewer: McDonough, Brian MD Last Annual Review Date: Apr 4, 2011 Copyright: © Copyright 2011 Health Grades, Inc. All rights reserved. May not be reproduced or reprinted without permission from Health Grades, Inc. Use of this information is governed by the HealthGrades User Agreement.

This Article is Filed Under: Bones, Joints and Muscles


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