Cushing's Syndrome

What is Cushing’s syndrome?

Cushing’s syndrome is caused by abnormally high levels of the hormone cortisol. Cortisol is commonly known as the “stress hormone” and is secreted by the adrenal glands, two small glands that lie on top of the kidneys. Cortisol plays an important role in a variety of processes and functions in the body including:

• Blood pressure regulation

• Heart and blood vessel function

• Proper metabolism and use of insulin, a hormone required to break down sugars for energy

• Stress and anxiety response

High levels of cortisol can impair the function of hormones in the body, which results in a variety of symptoms including a moon-faced appearance, upper body obesity, and fatigue. Cushing’s syndrome is treatable and even curable in many cases.

Complications of untreated Cushing’s syndrome can be serious and include hypertension, osteoporosis and diabetes. Seek prompt medical care if you have symptoms of Cushing’s syndrome, such as weight gain in the upper body, fatigue, and the development of unusual roundness of the face.