What is chronic kidney disease?

Chronic kidney disease is a disease in which the kidneys stop working over time. This means that waste and excess water are not properly removed from the bloodstream. The disease commonly affects people with diabetes and high blood pressure, but can affect others as well. Two in every 1,000 people in the United States have chronic kidney disease (Source: NIH).

Chronic kidney disease is progressive, meaning that it worsens over time. You may not experience any symptoms in the early stages of chronic kidney disease. As the disease progresses, you may experience symptoms such as fatigue, general feelings of illness, headaches, unexplained weight loss, and nausea. Middle stage symptoms include pain, confusion, muscle twitching, numbness and tingling, bad breath, bruising, bleeding, unusual thirst, sleep disorders, edema (swelling), and vomiting. The last stage of chronic kidney disease is known as end stage renal disease, or kidney failure.

Treatment for chronic kidney disease includes medications, such as angiotensin receptor blockers (to lower blood pressure) or phosphate binders (medications that prevent dangerously high levels of phosphorus in the body). Iron supplements may be used to prevent anemia (low red blood cell count), and other supplements may be useful in boosting depleted vitamin levels. Once chronic kidney disease has progressed to its final stages, dialysis or even kidney transplant may be necessary.

While there is no cure, chronic kidney disease can be managed. If you suspect you may have chronic kidney disease, it is vitally important to seek prompt medical care to retard progression of the disease. Changes in your lifestyle, such as eating a healthy diet, exercising regularly, and avoiding smoking, may also help prevent or control chronic kidney disease.

Seek immediate medical care (call 911) if you, or someone you are with, have serious symptoms, such as confusion, easy bleeding or bruising, difficulty breathing, inability to urinate, or bloody stool.

Seek prompt medical care if you have persistent symptoms of chronic kidney disease or if, for any reason, you suspect you may have chronic kidney disease. Early diagnosis requires simple blood and urine tests, and is critical for ensuring a good outcome.

SYMPTOMS

What are the symptoms of chronic kidney disease?

Symptoms of chronic kidney disease are related to the body’s inability to eliminate waste and excess water. Symptoms are progressive, meaning that they get worse over time. In fact, early stage chronic kidney disease may not manifest any symptoms. End stage chronic kidney disease, classified as end stage renal failure, involves symptoms that are very serious, even life threatening.... Read more about chronic kidney disease symptoms

CAUSES

What causes chronic kidney disease?

Chronic kidney disease is caused by damage to the kidneys over time. Usually, damage to the kidneys results from high blood pressure or poorly controlled diabetes. Damage to the kidneys may also result from problems with the circulatory system; kidney disorders, such as kidney stones; certain medications; environmental toxins; injury; or autoimmune disorders. The damaged kidneys become increasingly inefficient at filtering waste and excess water from the body, which can cause the disease to worsen.... Read more about chronic kidney disease causes

TREATMENTS

How is chronic kidney disease treated?

Chronic kidney disease can be treated with medications designed to slow and minimize damage to the kidneys. If chronic kidney disease progresses to end stage renal disease, dialysis or kidney transplant may be necessary to properly remove waste and excess water from the bloodstream.... Read more about chronic kidney disease treatments

Medical Reviewer: All content has been reviewed by board-certified physicians under the direction of Rich Klasco, M.D., FACEP. Last Annual Review Date: May 2, 2011 Copyright: © Copyright 2011 Health Grades, Inc. All rights reserved. May not be reproduced or reprinted without permission from Health Grades, Inc. Use of this information is governed by the HealthGrades User Agreement.

This Article is Filed Under: Kidneys and the Urinary System


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