What are the symptoms of amyloidosis?

Specific symptoms of amyloidosis will depend on which organs are affected by the disease. This can make diagnosis particularly challenging in secondary amyloidosis because the underlying disease, disorder or condition may have similar symptoms.

General symptoms of amyloidosis include:

  • Anemia (low red blood cell count)

  • Clay-colored stools

  • Fatigue

  • Joint pain

  • Numbness or tingling in the arms or legs

  • Skin changes

  • Swollen tongue

  • Unexplained weight loss

  • Weakness

Serious symptoms that might indicate a life-threatening condition

Amyloidosis can lead to serious and potentially life-threatening complications. Seek immediate medical care (call 911) if you, or someone you are with, have amyloidosis and any of the following symptoms:

  • Change in level of consciousness or alertness, such as passing out, fainting, confusion, or disorientation

  • Decreased or no urine output

  • Difficulty breathing or shortness of breath

  • Irregular heartbeat or palpitations

  • Persistent swelling of the ankles or other body parts

  • Severe dizziness

  • Swollen tongue

  • Uncontrolled bleeding

  • Unusual or sudden weakness or numbness


What is amyloidosis?

Amyloidosis is a group of diseases in which abnormal proteins, called amyloids, accumulate in the body and cause problems with bodily functions. Amyloidosis is not a form of cancer, but it is a serious condition.... Read more about amyloidosisintroduction


What causes amyloidosis?

The specific types of amyloidosis and the underlying cause are listed below.... Read more about amyloidosiscauses


How is amyloidosis treated?

Amyloidosis is a chronic condition. Treatment depends on the type of amyloidosis, your overall health, your treatment preferences, and the presence of any underlying diseases, disorders or conditions. All treatments have risks and benefits. Your health care provider is best able to guide your treatment decisions based on your specific circumstances.... Read more about amyloidosistreatments

Medical Reviewer: McDonough, Brian, MD Last Annual Review Date: Jun 27, 2011 Copyright: © Copyright 2011 Health Grades, Inc. All rights reserved. May not be reproduced or reprinted without permission from Health Grades, Inc. Use of this information is governed by the HealthGrades User Agreement.

This Article is Filed Under: Infections and Contagious Diseases

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